Formal Name CENPA
ChromDB ID HTR515
Entrez GeneID 1058
Taxonomy Link Homo sapiens (human)
ChromDB Taxon Eukaryotes; Opisthokonts; Animals; Bilateria; Deuterostomia; Chordata; Gnathostomata; Mammalia
Protein Group Histone H3 Family
Description CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms (summary or Entrez GeneID: 1058).
Gene Ontology
Biological Process
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Molecular Function
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Cellular Component
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ChromDB Model Type Transcript-NCBI RefSeq
Sequences
Transcript View